Intratympanic Gentamicin for the Treatment of Unilateral Meniere???s Disease
نویسندگان
چکیده
منابع مشابه
Intratympanic application of gentamicin for treatment of Menière's disease.
Since 1974 we have treated 118 patients suffering from unilateral and bilateral (two patients) Morbus Meniere with intratympanal applications of gentamicin-sulfate. In contrast to earlier attempts using this method, we did not try to destroy the vestibular apparatus, but taking into our considerations the recent findings about the pathophysiological mechanism of Morbus Meniere, only to damage t...
متن کاملIntratympanic treatment of intractable unilateral Meniere disease: gentamicin or dexamethasone? A randomized controlled trial.
OBJECTIVE To determine the efficacy and safety of low-dose intratympanic gentamicin (ITG) compared with intratympanic dexamethasone (ITD) in patients with intractable unilateral Ménière disease (MD). STUDY DESIGN Open prospective randomized controlled study. SETTING Tertiary referral center. SUBJECTS AND METHODS Sixty patients affected by definite unilateral MD were enrolled between Janua...
متن کاملIntratympanic gentamicin for Ménière's disease or syndrome.
BACKGROUND Ménière's disease is characterised by three major symptoms: vertigo, deafness and tinnitus, which may be accompanied by aural fullness, all of which are discontinuous and variable in intensity. While discontinuous, these symptoms are synchronous. Intratympanic application of gentamicin, an ototoxic aminoglycoside, is a relatively new ablative treatment for vertigo in Ménière's diseas...
متن کاملIntratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo.
Titration therapy with intratympanic gentamicin offers class A or B control of vertigo in 87% (range, 75%-100%) of patients with unilateral Ménière's disease. The risk of additional hearing loss is about 21% (range,0-37%). Vertigo may recur, however, in nearly one third of patients over time. These recurrences can also be treated by intratympanic gentamicin with a similar risk of hearing loss. ...
متن کاملVestibular nerve section versus intratympanic gentamicin for Meniere's disease.
OBJECTIVES/HYPOTHESIS Vestibular nerve section and transtympanic gentamicin administration are procedures with proven efficacy in the treatment of vertigo associated with Meniere's disease refractory to medical management. Hearing loss is a known complication of each of these procedures; however, there has not been a report of hearing results of both treatments from a single institution. STUD...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 2000
ISSN: 0023-852X
DOI: 10.1097/00005537-200008000-00014